The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...

The US Environmental Protection Agency (EPA) plans to abandon landmark regulations limiting airborne mercury and greenhouse ...

Over the past decade, several novel immunotherapies have transformed the treatment landscape of relapsed or refractory B-cell acute lymphoblastic leukaemia. In the pivotal TOWER trial, blinatumomab—a ...

The administration of US President Donald Trump has launched a full-fledged assault on science and public health;1 its “flood the zone” strategy created chaos and initially overwhelmed potential ...

Physicians treating patients with Crohn's disease face a plethora of drug choices. Yet, overall rates of clinical response seem stable over time,1 suggesting the existence of a therapeutic ceiling ...

Solid organ transplantation provides life-saving and life-enhancing treatments for patients with end-stage organ failure.1,2 However, the rising global burden of non-communicable diseases (NCDs) and ...

Advances in solid organ transplantation, such as improved organ preservation technologies and novel approaches to immunosuppression management, have the potential to improve outcomes in transplant ...

It was by far the most difficult phone call of my life. Absolutely nothing can prepare you for telling your mother that she ...

The relationship between hormone therapy (oestrogen with or without progestogen) and breast cancer risk has been widely ...

We read with great interest the Lancet Oncology Editorial1 calling for a coordinated global approach to address the growing ...

We read with great interest the published results of the RADIOSA trial by Giulia Marvaso and colleagues.1 This well designed ...

Negotiations are ongoing in New York to agree the latest UN political declaration on non-communicable diseases (NCDs) and ...