Transferrin-receptor shuttles distribute antibody cargo throughout the parenchyma, steering clear of ARIA-provoking vascular amyloid. Trontinemab is enrolling Phase 3 for early AD, announces plans for ...

Somewhere, a synapse fires. Sodium and calcium flood the dendrite and trigger transcription of genes necessary for learning and memory. Within minutes, the transport protein Arc reaches the dendrite ...

This brain bank stores frozen tissue. All donations go in through the lab's clinical core, and have been tested and diagnosed. The lab shares brain tissue through its biospecimen core.

The center accepts brain donations from Alzheimer's patients and cognitively normal controls who were seen at the center before death (family members can call the office to discuss feasibility of ...

Microdissection of more than 130 different brain nuclei is performed on frozen brains. These samples are approved for neurochemistry, neuroendocrine, molecular biology, proteomic and genomic studies.

Funding Level 1: $0.3M total costs. Funding Level 2: $1.0M total costs. Pre-Application (Letter of Intent) Submission Deadline: 5:00 p.m. Eastern Time (ET), October ...

This center only accepts brain tissue from patients evaluated, tested, and treated in its clinic for several years. The center keeps both healthy and diseased brains, but has more of the latter. It is ...

Pre-Application (Letter of Intent) Submission Deadline: 5:00 p.m. Eastern Time (ET), October 23, 2026. Application Submission Deadline: 11:59 p.m. ET, November 6, 2026.

The brain bank houses one of the most extensive collections of human brain tissue in the southern hemisphere, comprising nine different neurological diseases such as Alzheimer’s, Huntington’s, ...

Lomecel-B is a preparation of multipotent stem and progenitor cells isolated from donated bone marrow of young healthy adults, and expanded in culture. The cells are administered by intravenous ...

Two new ApoE variants turned up in American populations. Protective variant W276C discourages ApoE from oligomerizing. Risk variant R189C promotes its lipidation. Lipidated ApoE4 disrupts microglial ...

Could measuring proteins in the blood help pinpoint which genes underlie certain GWAS signals? By combining plasma proteomics data with genetic analyses, scientists led by Keenan Walker at the ...