The San Francisco 49ers return to Levi's Stadium to face the Los Angeles Rams in the second of two matchups this season. This ...

The 49ers resisted splashy trade rumors for Trey Hendrickson and others, choosing patience and long-term roster health over ...

BOX SCOREAt some point, the 49ers’ injury issues were going to catch up to them, and that was the case in their 42-26 loss to ...

Matthew Stafford extended his MVP campaign with 280 yards and four more touchdowns, pushing the Rams to 7-2. Los Angeles' ...

Matthew Stafford threw his 400th career touchdown pass, and the Rams blew out the 49ers 42-26 on Sunday.The Rams quarterback ...

Rams wide receiver Davante Adams left in the fourth quarter with what the team called a back injury. They listed him as ...

The 49ers (6-4) fell behind 21-0 early, yielded six touchdowns and produced no takeaways in a 42-26 loss to the ...

The realities of an injury-depleted roster were on display for the San Francisco 49ers on Sunday, and they weren't pretty.

Kyle Shanahan says Brock Purdy "could have gone" against the Rams but reveals why San Francisco chose caution with its QB.

ESPN analyst Dan Orlovsky believes the San Francisco 49ers may have a developing quarterback controversy on their hands.

San Francisco 49ers running back Brian Robinson Jr. powered his way into the end zone in the fourth quarter, contributing to ...

The 49ers are back in it.San Francisco, which trailed 21-0 early in the second quarter, has cut its deficit to 21-14 with ...