Mepolizumab is a monoclonal antibody that targets interleukin-5, a key cytokine in eosinophilic inflammation. The MATINEE ...

Objective Severe early-onset-chronic obstructive pulmonary disease (SEO-COPD) represents the most severe form of COPD that ...

A 62-year-old man with a history of systemic Amyloid light-chain (AL) amyloidosis in prior haematological remission presented with progressive dyspnoea and non-productive cough. He denied haemoptysis, ...

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A 19-year-old female presented with complaints of cough, dyspnoea and chest pain, which had been ongoing for approximately 2 weeks. On physical examination, the patient was afebrile and ...

Introduction Physical exercise has been used to assist smoking cessation, but supervised programmes are bounded by limited ...

Objective To determine the diagnostic accuracy of point-of-care ultrasound in suspected pulmonary embolism. Design Systematic review and meta-analysis. Data sources MEDLINE, Embase, CINAHL and ...

Introduction Oscillating positive expiratory pressure (OPEP) devices are intended to facilitate sputum clearance in chronic obstructive pulmonary disease (COPD), but there is uncertainty as to their ...

Purpose Malignant pleural mesothelioma (MPM) has a high symptom burden and poor survival. Evidence from other cancer types suggests some benefit in health-related quality of life (HRQoL) with early ...

Dr J B Soriano, Department of Worldwide Epidemiology, GlaxoWellcome R&D, Greenford, Middlesex UB6 0HE, UK email: jbs42397{at}glaxowellcome.co.uk BACKGROUND Recent trends in physician diagnosed chronic ...

These guidelines have been replaced by 2010 Guideline On Radical Management Of Patients With Lung Cancer and NICE Lung Cancer Guideline CG121 2011 Superseded By 2010 Guideline On Radical Management Of ...