The U.S. House of Representatives has passed legislation that would renew the ACT for ALS, a landmark federal law that supports amyotrophic lateral sclerosis (ALS) research and helps people with the ...

ALS-causing NEK1 gene mutations disrupt cellular protein production machinery. Truncated NEK1 protein accumulates in the nucleolus, impairing ribosome biogenesis. This disruption leads to cell death ...

RAG-17 is an experimental RNA-targeting therapy designed to lower toxic SOD1 protein in people with SOD1-ALS. A six-person trial found RAG-17 was well tolerated, with no serious side effects. RAG-17 ...

The Muscular Dystrophy Association (MDA) brought its Engage Community Seminar to Hershey, Pennsylvania, on July 18, uniting ...

A new genetic study links higher levels of specific fat molecules to increased ALS risk. Fat metabolism in the body was identified as a relevant pathway in ALS susceptibility. The scientists say ...

While the findings align with previous research linking smoking to ALS, researchers found no consistent evidence that heavier ...

An AI-powered brain implant helped an ALS patient regain speech by decoding brain signals. This neuroprosthesis translates ...

Bulbar-onset ALS is diagnosed about four months sooner than limb-onset ALS. Limb-onset ALS is often misdiagnosed, delaying critical treatment and care. Awareness strategies for limb-onset ALS can ...

Of all the scenes that stay in my mind from my late husband Jeff’s time with ALS, this is among the most enduring: Jeff, wearing a Navy baseball cap and a weathered T-shirt, sitting behind the console ...

While genetics alone do not cause amyotrophic lateral sclerosis (ALS), a large number of genetic mutations have been associated with the neurodegenerative disease. Such mutations can increase a person ...

A less invasive brain-computer interface is being developed to help people with impaired speech, including ALS, communicate. Fluent’s device would sit under the scalp but outside the skull, which the ...