Detroit, the Lions
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The Bills will host the Detroit Lions for Thursday Night Football in week two of the upcoming NFL season.The rest of Buffalo’s schedule including their week one contest has not been announced. This week two clash with the Lions will be the first regular season game at the new Highmark Stadium.
The Buffalo Bills will host the Detroit Lions in the first game at Buffalo's new Highmark Stadium. Here's when:
The Detroit Lions will have at least one primetime game on their 2026 NFL schedule. The NFL announced on Monday that the Lions will face off against the Buffalo Bills in Week 2 for a “Thursday Night Football” matchup. There are a couple of notable things about this matchup for the Lions and Bills.