Recombinant DNASE1L3 therapy reduced symptoms in a patient with severe lupus with DNASE1L3 deficiency. Antidrug antibodies caused effects to wane, but findings support NET-targeted therapy as a ...

A patient with type 1 diabetes received genetically modified allogeneic islets and no immunosuppression. Results obtained ...

Aspirin after an initial short course of rivaroxaban has been shown to be safe and effective for the prevention of venous thromboembolism after total hip or total knee arthroplasty, but uncertainty ...

Caring for undocumented immigrants at a time of heightened fear requires actionable frameworks guided by compassion and respect. Trauma-informed care is a vital approach for physicians.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 15).

Colliding Forces — The Aging of the Baby Boom Generation and Contracting Nursing-Home Supply. M.A. Unruh , V. Mor , and H.-Y. Jung ...

The two academic authors of the article by Jayne et al., Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609, 1 request retraction of the article because, according ...

The United States faces a projected shortage of millions of long-term–care workers by 2040. Yet in each area where progress could help address this gap, federal policy is moving in the wrong direction ...

Five of the 56 signatories of the American Declaration of Independence were doctors, a high-water mark in the history of medical representation in American political leadership. This is the third in a ...

In 832 patients with rare genetic disease, a conclusive diagnosis was made for 160 patients (19.2%) with long-read genome sequencing and for 137 patients (16.5%) with standard-of-care testing.

A rapid growth in the population of older Americans has long been anticipated. But projections didn’t anticipate that this transition would coincide with a sustained reduction in nursing-home services ...

To the Editor: In the phase 3 GRADUATE trials of gantenerumab for early Alzheimer’s disease reported by Bateman et al. (Nov. 16 issue), 1 participants receiving gantenerumab had a greater decrease in ...