The EMBO Journal

New plastids, old proteins: repeated endosymbiotic acquisitions in kareniacean dinoflagellates

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...
The EMBO Journal

A ‘rich-get-richer’ mechanism drives patchy dynamics and resistance evolution in antibiotic-treated bacteria

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Global resource competition and local ...
The EMBO Journal

Palmitoylation by ZDHHC4 inhibits TRPV1-mediated nociception

Transient receptor potential vanilloid 1 (TRPV1) is a capsaicin-sensitive ion channel implicated in pain sensation. While TRPV1 potentiation in hyperalgesia development has been extensively ...
The EMBO Journal

Constructive correction

A fundamental tenet of the scientific process is that science is self‐correcting. Efficient correction of the scientific literature requires a more nuanced set of policies and tools that lower the bar ...
The EMBO Journal

Cost and availability of novel cell and gene therapies: Can we avoid a catastrophic second valley of death?

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.
The EMBO Journal

Machine learning identifies key metabolic reactions in bacterial growth on different carbon sources

Carbon source-dependent control of bacterial growth is fundamental to bacterial physiology and survival. However, pinpointing the metabolic steps important for cell growth is challenging due to the ...
The EMBO Journal

MitoStores : a place for precursors to ride out the storm

This cover highlights the article DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma by Clara Taffoni, Johanna Marines, Nadine Laguette and ...
The EMBO Journal

STINGing organelle surface with acid

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) innate immune pathway has emerged as a critical driver of inflammation in a variety of settings, such as virus infection, ...
The EMBO Journal

Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells

This month's cover highlights the article Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM‐1 by Max Grönloh, Janine Arts, Jaap van Buul and ...
The EMBO Journal

Once in a lifetime

Most senior scientists who have carved out a career in science eventually look back at how they managed to get there. Many may feel that their position is a just reward for their hard work and ...
The EMBO Journal

Stoichiometry of the T‐cell receptor–CD3 complex and key intermediates assembled in the endoplasmic reticulum

The T‐cell receptor (TCR)–CD3 complex is critical for T‐cell development and function, and represents one of the most complex transmembrane receptors. Models of different stoichiometry and valency ...
The EMBO Journal

The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation

Naïve T helper (Th) cells differentiate in response to antigen stimulation into either Th1 or Th2 effector cells, which are characterized by the secretion of different set of cytokines. Th2 ...