Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Teneurins are conserved cell adhesion ...
The T‐cell receptor (TCR)–CD3 complex is critical for T‐cell development and function, and represents one of the most complex transmembrane receptors. Models of different stoichiometry and valency ...
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...
Figure 3. NRIF is polyubiquitinated by the E3 ubiquitin ligase TRAF6. HEK 293 cells were cotransfected with Flag‐NRIF, Flag‐TRAF6 or HA‐ubiquitin, then lysed in SDS lysis buffer and the lysates were ...
Department of Microbiology and Division of Developmental and Clinical Immunology, University of Alabama at Birmingham, Birmingham, AL, 35294-3300 USA ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. T‐box family transcription factors have ...
The fission yeast cell‐polarity regulator tea1p is targeted to cell tips by association with growing microtubule ends. Tea1p is subsequently anchored at the cell cortex at cell tips via an unknown ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Auxin dictates root architecture via the Auxin ...
The human body strives to control the concentration of blood glucose within a narrow range, by using counterbalancing hormones. When we ingest sugar, the surge in blood glucose triggers the release of ...
Nonsense‐mediated mRNA decay (NMD) is an mRNA surveillance pathway that recognizes and degrades aberrant mRNAs containing premature stop codons. A critical protein in NMD is Upf1p, which belongs to ...
Heterozygous DT40 cells with one TRX‐2 allele disrupted with TRX‐2–HisR were transfected. DT40 cells were transfected with the indicated plasmids and drug‐resistant clones were analyzed for homologous ...
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