Background Effective management of coexisting heart failure (HF), chronic kidney disease (CKD) and type 2 diabetes mellitus ...

Original research: Mortality associated with moderate and severe mitral regurgitation in 608 570 men and women undergoing ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with persistent undertreatment of high-risk older patients with effective ...

Implantation of drug-eluting stents (DESs) remains central to percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS) and chronic coronary syndromes (CCS). DES platforms, polymers ...

Introduction Cardiovascular diseases (CVD) accounted for an alarming 17.9 million deaths globally in 2019. Acute coronary syndrome (ACS) is often the most common initial presentation of CVD. ACS ...

2 Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 3 Epidemiological Cardiology Research Center (EPICARE), Department of Epidemiology and ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergency surgery to avert fatal outcome. Conventional surgical procedures comprise excision of the entry tear and ...

Objective Troponin and B-type natriuretic peptide (BNP) concentrations are associated with cardiovascular risk in stable patients. Understanding their determinants and identifying modifiable clinical ...

Introduction Pulmonary vein isolation (PVI) is an established therapeutic strategy for atrial fibrillation (AF). Recent advancements in AF ablation have led to the development of the novel pulsed ...