Teddi Mellencamp opened up about her mental and physical health ahead of a 'week of radiation' treatment in a series of candid Instagram videos in March 2025. Mellencamp previously shared that doctors had found multiple tumors in her brain in February.

The reality TV star underwent emergency surgery last month after being admitted to the hospital due to “severe and debilitating headaches.”

Teddi Mellencamp was diagnosed with melanoma in 2022. Since then, she's had multiple biopsies, surgeries and the cancer has metastasized to her brain and lung.