Background Effective management of coexisting heart failure (HF), chronic kidney disease (CKD) and type 2 diabetes mellitus ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with ...

Background There is substantial interest in the cardiovascular effects of e-cigarette use, highlighting the need to update our knowledge on the subject. We conducted this review to analyse whether ...

Background and aims In the primary prevention setting, low-dose aspirin reduces major vascular events (MVEs) by approximately 11% but increases major bleeding (MB) by 40–50%, implying that net benefit ...

Background Menopause is a timely opportunity to screen for cardiovascular disease (CVD) and intervene with healthier lifestyles. We investigated the association between premature/early menopause and ...

Introduction UK and US Guidelines now recommend HeartFlow FFR-CT (Fractional Flow Reserve-Computed Tomography) in stable chest pain (CP), but its clinical effectiveness and costs in real-world ...

Influence of depression trajectories in heart failure patients with preserved ejection fractions: a secondary analysis of adverse outcomes in the TOPCAT trial ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Objective To assess the long-term functional and health-related quality-of-life (HRQoL) outcomes for out-of-hospital cardiac arrest (OHCA) survivors stratified by initial defibrillation provider.