In this Avera Medical Minute, learn how CAR T-cell therapy is now being tested for use in other non-cancerous conditions.

SIOUX FALLS, S.D. (Dakota News Now) - Kids at a Sioux Falls summer camp are getting way closer to the critters than most of ...

With the competition season right around the corner, Calvary Elite Gymnastics is racing to recover after storm damage hit ...

SIOUX FALLS, S.D. (Dakota News Now) - A Sioux Falls nonprofit is getting a major boost to continue helping people across the region. Team Buche Cares received a surprise $25,000 donation through First ...

The Sioux Falls police department has released the names of a married couple that was found dead in southwest Sioux Falls ...

SIOUX FALLS, S.D. (Dakota News Now) - The Furniture Mission of South Dakota is introducing a new event. Janean Michalov and ...

For most of the viewing area, it will be a much quieter day; however, an isolated severe weather threat may return for ...

Governor Larry Rhoden has formally requested a presidential major disaster declaration for eight South Dakota counties and ...

SIOUX FALLS, S.D. () - A Sioux Falls man is behind bars after attacking and robbing a woman late Sunday night. According to ...

Following Saturday’s severe storms in eastern South Dakota, especially in the Sioux Falls area, residents and businesses are ...

Following Saturday’s severe storms in eastern South Dakota, especially in the Sioux Falls area, residents and businesses are ...

Here’s what Minnehaha County election officials say has changed since the last election — and what voters should know before ...