Potential immune evasion mechanism identified in premalignant lung lesions

Throughout a person's lifetime, the cells lining the respiratory tract are exposed to inhaled pollutants, including cigarette ...
Technology Networks

How Early Lung Damage Slips Past the Immune System

Researchers identified miR-149-5p as overexpressed in progressive bronchial premalignant lesions. The microRNA suppresses ...
Phys.org

Biologists warn of potential errors in microRNA overexpression method

"Our study has shown that only sequencing can reveal the shift in the cleavage position. Unfortunately, sequencing is a relatively expensive method, and not all laboratories can afford it. Therefore, ...
ascopubs.org

Constructing a machine learning-based non-invasive liquid biopsy model for lung cancer detection via miRNA sequencing.

Assessment of carcinoembryonic antigen-related cell adhesion molecule 5 expression by immunohistochemistry in real-world clinical samples of non-small cell lung cancer. This is an ASCO Meeting ...
The Scientist

Profiling MicroRNA from Poo to Understand Gut Health and Disease

Fascinated by the big impact of these small molecules, microbiologist Emma Layton wanted to study fecal microRNAs as part of her graduate studies at The University of Manchester. However, she ran into ...
C&EN

Two share Nobel Prize in Physiology or Medicine for microRNA discoveries

American biologists Victor Ambros from the University of Massachusetts and Gary Ruvkun from Harvard University have won the 2024 Nobel Prize in Physiology or Medicine. They share the prize for their ...
Yahoo

MicroRNA − a new Nobel laureate describes the scientific process of discovering these tiny molecules that turn genes on and off

How did you start thinking about this fundamental question at the heart of the discovery of microRNA, about how cells get the instructions to do what they do? It was well understood that proteins ...
The Conversation

MicroRNA − a new Nobel laureate describes the scientific process of discovering these tiny molecules that turn genes on and off

Victor Ambros receives funding from the U.S. National Institutes of Health. The Conversation Weekly podcast caught up with Victor Ambros from his lab at the UMass Chan Medical School to learn more ...