Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most ...

Cryo-EM revealed HIV-1 integrase’s distinct structures as it shifts between its two roles of DNA integration and RNA-binding.

Researchers at the VIB-VUB Center for Structural Biology have developed a new microfluidics-based workflow that enables ...

The researchers captured eight unique structural models and 16 cryogenic electron microscopy maps of the receptor with both ...

Machine learning (ML) and artificial intelligence (AI) methodologies are having a revolutionizing impact in advancing ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Structure-based designs facilitate drug discovery, and cryogenic electron microscopy (cryo-EM) is an increasingly important tool to determine high-resolution structures of proteins and protein ...

The first full-length structures of the human angiotensin-converting enzyme (ACE) have been determined by researchers from the University of Cape Town (UCT) using cryo-electron microscopy (cryo-EM).