Spinal muscular atrophy (SMA) is a genetic neuromuscular disease affecting specialized nerve cells that control voluntary muscle movement, according to the Muscular Dystrophy Association (MDA). It can ...

Designation is supported by an exploratory analysis from the Phase 1b study showing that some children with SMA previously treated with gene ...

The FDA's decision follows data from a Phase Ib study on salanersen.

Forbes contributors publish independent expert analyses and insights. Spinal muscular atrophy affects the nerves that control muscle movement, leading to progressive weakening. As a result, infants ...

Six weeks of resistance training with a new wearable device more than doubled spinal muscular atrophy patients' leg strength, ...

Ancient bacteria that have evolved to become integral to our cells—converting nutrients from food into energy—may also contribute to neurologic disorders, such as spinal muscular atrophy (SMA) and ...

Spinal muscular atrophy (SMA) is a genetic, progressive neuromuscular disorder. SMA affects muscle-controlling nerve cells, called motor neurons, in the spinal cord. The condition leads to muscle ...

"Managing pain in patients with SMA begins with the recognition that there are predictable etiologies leading to pain in SMA and investigating them during each medical visit is important to implement ...

Spinal muscular atrophy (SMA) is a progressive neurodegenerative disorder set in motion before birth. Scientists at St. Jude Children's Research Hospital led the first in uterotreatment of SMA with ...

A local family has a personal stake in the donations that pour into St. Jude Children’s Research Hospital. Every month, the ...

—The slow progression of SMA in adults and older children complicates evaluation of treatment response to newer therapies. Longitudinal quantitative MRI (qMRI) may give clinicians a better handle on ...