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Inhibiting programmed cell death to treat a rare childhood disease

A team of researchers at the University of Cologne's Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...
Labmate Online

Pre-surgery pembrolizumab has success clearing tumours in most patients with desmoplastic melanoma, trial reports

Investigators have reported that three doses of the anti-programmed cell death protein 1 immunotherapy pembrolizumab – given ...
Cancer Therapy Advisor

FDA Grants Priority Review to Datopotamab Deruxtecan for Metastatic TNBC

Phase 3 trial data show datopotamab deruxtecan reduces the risk of disease progression or death in patients with metastatic TNBC.
News Medical

Scientists gain new insights into protein network that regulates programmed cell death

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases. Joint press release by the ...
ascopubs.org

PD-1 inhibitors versus PD-L1 inhibitors in PD-L1–negative advanced non-small cell lung cancer: A meta-analysis of survival outcomes.

Predictive value of the triglyceride-glucose index for the efficacy of immunotherapy in patients with advanced NSCLC: A retrospective study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...