Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

Liquid cell electron microscopy (LC-EM) has emerged as a transformative tool for observing nanoparticles in their native, fluid environment with nanometre spatial resolution and millisecond temporal ...

Basic techniques for observing the microscopic structure of the human body —Histology is the study of understanding the human ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase-contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the seventeenth century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and ...

Adapted from an article by Robert Sanders at UC Berkeley. Nearly 100 years ago, a discovery revolutionized light microscopy. The introduction of the phase-contrast microscope, which garnered a Nobel ...

A team of researchers has developed the first transmission electron microscope which operates at the temporal resolution of a single attosecond, allowing for the first still-image of an electron in ...

Beauty and mystery—it is hard to imagine a more alluring combination, and this is precisely what we encounter when we observe phenomena in the nanoworld. But are we really sure that observations made ...

Researchers at the University of Arizona have developed the world’s fastest electron microscope, capturing electron motion in real-time at an astonishing temporal resolution of just 1 attosecond. Al ...