The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Muscle cramps are a common and often uncomfortable phenomenon that many individuals experience. These sudden, involuntary contractions can occur in various muscle groups, causing sharp pain and ...

Researchers were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction. Although in the early stages, the research ...

A new molecular pathway has been identified that is critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. Researchers at UMass Medical ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

The ability to modify the intracellular concentrations of divalent calcium ions is vital to normal cell functioning. In the cells of the cardiac muscle, calcium ions play a crucial role in coupling ...

IT is well established that an increase in the intracellular concentration of ionized calcium after excitation in the membrane is the key factor for initiation of contraction of various types of ...

You’re relaxing on the sofa when suddenly your eyelid starts twitching. Or perhaps it’s a muscle in your arm, your leg, or your foot that begins to spasm – sometimes for a few seconds, sometimes for ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...