Business Wire

GM-CSF Knock-out CAR-T Study Published in Peer-Reviewed Journal Leukemia

GM-CSF Knock-out CAR-T Study Published in Peer-Reviewed Journal Leukemia CRISPR/Cas9-Mediated GM-CSF knock-out (GM-CSF ko) CAR-T cells demonstrate reduced apoptosis and enhanced in vivo anti-tumor ...
ascopubs.org

Novel use of MR spectroscopy in detecting CSF lactate for diagnosis of neoplastic meningitis.

A pharmacokinetic (PK) study of AC480 administered twice daily in patients with surgically resectable, recurrent malignant glioma (MG) not on enzyme-inducing antiepileptic drug (EIAED). Background: ...
ascopubs.org

Systematic Review of Cerebrospinal Fluid Biomarker Discovery in Neuro-Oncology: A Roadmap to Standardization and Clinical Application

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...
ALZFORUM

Study Finds Sex Influences CSF Tau Levels in ApoE4 Carriers

The apolipoprotein E4 (ApoE4) allele, the strongest known genetic risk factor for late-onset sporadic Alzheimer’s disease, puts women at higher risk for the disease than men, but how remains unclear.
Medscape

CSF Inflammatory Markers Tied to Brain Alterations in SARS-CoV-2

The study covered in this summary was published in medRxiv.org as a preprint and has not yet been peer reviewed. Cerebrospinal fluid (CSF) inflammatory marker levels were found to be associated with ...
News Medical

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

In a recent study published in Jama Network, researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF). Study: Viral Antigen and ...