Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods rely on adhesive or mechanical forces to hold and scan cells, which limit ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

Recent advances in fluorescence microscopy techniques and tissue clearing, labeling, and staining provide unprecedented opportunities to investigate brain structure and function. These experiments’ ...

Cryo-correlative light and electron microscopy (cryoCLEM) is a powerful strategy to high resolution imaging in the unperturbed hydrated state. In this approach fluorescence microscopy aids localizing ...

I built a 3D printed, scanning laser confocal microscope so I could collect 3D surface topology and profilometry data! The ...

Over the last two decades, microscopy has seen unprecedented advances in speed and resolution. However, cellular structures are essentially three-dimensional, and conventional super-resolution ...

The developed high-speed three-dimensional scanning force microscopy enabled the measurement of 3D force distribution at solid-liquid interfaces at 1.6 s/3D image. With this technique, 3D hydration ...

Laser-driven thermoviscous flows provide contact-free rotation, transport or stabilization of delicate samples such as ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Small Methods the 3D imaging of a suspended nanostructure. The technique used is an extension of atomic force ...

Researchers developed a large-scale, dynamic imaging technique using mesoscopic oblique plane microscopy, which can capture 3D images of entire organisms and maintain cellular resolution. A new ...

Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish feats that neither could have done on its own. Such is the case with a hybrid ...