Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...
An enzyme that controls the maturation and long-term survival of immune cells called macrophages has been discovered, with implications for research on aging and inflammatory disease. Virtually all ...
Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...
Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...
Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...
Cancer treatment has made great progress over the past few decades, but many solid tumors remain very difficult to treat.
Visceral fat is the fat stored deep in the abdomen around internal organs. It is strongly linked to inflammation and to higher risk of insulin resistance and type 2 diabetes. Inflammation in fat ...
Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.