Introduction Critically ill patients commonly develop acquired neutrophil dysfunction, which increases susceptibility to intensive care unit-acquired infection (ICU-AI). This study aimed to assess ...

Early interferon therapy reduces secondary myelofibrosis risk in young ET and PV patients. Cytoreductive drugs do not lower thrombotic event risk in young patients. Elevated white blood cell ...

All participants developed durable anti-AAV5 antibodies, and cellular immune responses specific for the AAV5 capsid were detected in most participants by interferon-g enzyme-linked immunosorbent ...

Interferons are also extremely diverse, and have redundancies among them. Should one flavor get flummoxed by a pathogen, another would likely help fill in the gaps.

In mice with an intact immune system, alpha-synuclein overexpression in the mouse model resulted in increased numbers of CD4+ T-cells that were also positive for the transcription factor T-bet, along ...

An injection of a type of interferon drastically reduced the risk of severe COVID in a late-stage trial ...

After his best friend from high school had a daughter with Down syndrome, immunologist Dusan Bogunovic of the Icahn School of Medicine at Mount Sinai in New York pored over decades of research to ...

How quickly an infected person pumps out interferons may not matter as much these days, when most people have already been infected with the virus or vaccinated against it, Iwasaki says.

Alzheimer’s disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities. Although scientists do ...