UK-based DefiniGEN has developed iPSC-derived cell lines that can replace primary human hepatocytes for toxicity testing and accelerate the development of novel liver-targeted therapeutics. Drugmakers ...

The increasing need to evaluate chemical safety without relying on animal models has driven the refinement and diversification of in vitro cytotoxicity assays. These tests involve exposing cultured ...

So many chemicals to test, so little resources and time. Adam Gault/OJO Images via Getty Images A vast number of chemicals are registered for production and use around the world. But only a portion ...

Well before a human receives the first dose of an experimental drug, it’s evaluated in an animal to test for toxicity. Monkeys are often chosen for their genetic similarities to humans, and safe ...