Synthetic gene expression in engineered cells typically depends on the host cell’s limited pool of intracellular resources, which can lead to resource competition between native and engineered ...
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...