By Hugo Francisco de Souza A new plasma biomarker clock offers an early glimpse into Alzheimer’s timing, potentially reshaping prevention research and therapeutic trials. Study: Predicting onset of ...

For decades, animal and 2D cell models have been the backbone of biomedical research and drug development, laying the foundation for many of the medical advances that we benefit from today. But these ...

While further validation will be required, these findings suggest that plasma p-tau217 clocks could provide a practical and ...

Modelling teams from academia, public health, the private sector or other backgrounds are warmly invited to participate. Participation is free. The HPAI Modelling Challenge addresses the urgent need ...

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...

A major new initiative involving Leicester experts aims to redefine human-based research models for greater understanding of disease and the acceleration of new medicines. The joint £15.9 million ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

The Chinese University of Hong Kong is preparing to extend its diabetes-focused risk prediction model into an Asia-wide chronic disease analytics platform, initially leveraging one of Asia’s largest ...

The National One Health Mission has invited Expressions of Interest from institutions to develop disease modelling programmes for humans, livestock and wildlife. Selected organisations will receive ...

A study published in Molecular Psychiatry reveals a path of cause-effect molecular events that can lead to Alzheimer's disease (AD). Researchers at Baylor College of Medicine, Duncan Neurological ...