Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

Plasmids and the model bacterium Escherichia coli are at the heart of recombinant gene technologies. Plasmids are handled in test tubes with enzymes such as restriction endonucleases, ligases, and ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Using the Telomere-to-Telomere reference, we assemble the distribution of simple tandem repeat lengths present in the human genome. Analyzing over three hundred mammalian genomes, we find remarkable ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

With just a room-temperature “pot,” a sprinkling of molecules, and a simple electrical device, pathogen DNA detection can now be achieved in under an hour anywhere. This method creates ...