Centrosome abnormalities are hallmarks of various cancers and have been implicated in chromosome missegregation, chromosomal instability, and aneuploidy. Since genetic instability is a common feature ...
Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma
To investigate whether centrosome abnormalities contribute to chromosomal instability in NHL and to elucidate the possible biological consequences, we have investigated centrosome aberrations in 24 FL ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells. CD8 + T ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell's cytoskeleton. Centrosome dysfunction contributes to diseases like ...
Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...
Intra-patient genomic heterogeneity of single circulating tumor cells (CTCs) associated to phenotypic CTC heterogeneity in metastatic castrate resistant prostate cancer (mCRPC). SOD2 rs4880 CT/CC ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...
Researchers have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth and migration: ...
In humans and other mammals, cardiac muscle cells stop replicating soon after birth, unlike the cardiac muscle cells in, say, zebrafish and amphibians. What do zebrafish and amphibian cardiomyocytes ...
Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth ...
A tiny, freshwater flatworm found in ponds and rivers around the world that has long intrigued scientists for its remarkable ability to regenerate has now added a new wrinkle to biology. Reporting in ...
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