Though CAR T cells have been effective against certain blood cancers, they have not been for solid tumors. Now, a new form of ...

Antibody therapies work in part by binding to Fc receptors, proteins found on immune cells that control key immune functions such as antibody-mediated cell killing and inflammation. Since these ...

The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...

Though CAR T cells have been effective against certain blood cancers, they have not been for solid tumors. Now, a new form of highly sensitive CAR T ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

By Hugo Francisco de Souza A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune therapies could reshape future treatment ...

Many TNBC tumors exhibit elevated intracellular iron levels and heightened oxidative stress, creating a biological reliance ...

A stem-cell-based "organ-on-a-chip" model of ALS mimics early biological changes seen in the degenerative disease.

Why Antibody Therapies Fail in Late-Stage Testing. Antibody therapies work in part by binding to Fc? receptors, proteins ...