State-of-the-art AI model accurately predicting unseen biological experiments X-Cell is trained on X-Atlas/Pisces, the largest and most context-diverse genome-wide perturbation dataset ever reported ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

The human cell is a miserable thing to study. Tens of trillions of them exist in the body, forming an enormous and intricate network that governs every disease and metabolic process. Each cell in that ...

It's tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Physical pressure can stop cancer cells from growing large enough to divide, revealing why squeezed tumors may stall.

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...