Just a few millimeters thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the ...

Researchers found that extracellular vesicles from menstrual blood stem cells promoted cartilage regeneration and reduced ...

Current intra-articular drug delivery methods do not guarantee sufficient drug penetration into cartilage tissue to reach cell and matrix targets at the concentrations necessary to elicit the desired ...

Cartilage Oligomeric Matrix Protein (COMP) is a pentameric extracellular matrix glycoprotein that orchestrates collagen fibrillogenesis and maintains cartilage resilience. In healthy growth plates, ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal ...

In patients with severe osteoarthritis, cartilage can wear so thin that joints essentially transform into bone on bone — without a cushion between. A new therapy that uses synthetic nanofibers to ...

Stanford researchers have shown that blocking a single enzyme called 15-PGDH can regrow lost cartilage in aging mouse knees ...

More than 600 million people suffer from osteoarthritis—a progressive, degenerative joint disorder resulting in cartilage damage, loss of joint function, and chronic pain. 1 Treatments are often ...

Expedition 74 crew members aboard the International Space Station are 3D-printing viable human cartilage tissues inside the ...

A working group develops strategies for regeneration of articular cartilage and has found that natural cartilage matrix is suitable as a biomaterial for improved cartilage regeneration. Just a few ...

Cartilage cells generate more protein components (collagen II and aggrecan) for regeneration when treated with fast-moving dancing molecules (left) compared to slower moving molecules. In November ...