According to the Centers for Disease Control, the earliest warning signs of the primary stage of syphilis appear as sores at ...

Back by popular demand, the largest free concert series on the Central Coast will return to San Luis Obispo for its 29th season this summer with a jam-packed weekly line-up. The 2025 Concerts in the ...

Cal Poly and the City of San Luis Obispo are partnering on efforts to avoid another out-of-control St. Patrick's Day weekend block party through an on-campus concert.

One San Luis Obispo woman shared her struggle to find accessible, affordable housing after an accident last year left her disabled.

The Police Department was expecting to recommend charges to the San Luis Obispo County District Attorney’s Office this week, ...

A new wildfire was reported today at 7:08 p.m. in San Luis Obispo County. Springs Fire has been burning on private land. At ...

Two new state-of-the-art cancer centers are coming soon to San Luis Obispo County. The cities of San Luis Obispo and ...

Peachy Fire initially started today at 3:43 p.m. in San Luis Obispo County. It has burned 0.3 acres of private land after ...

That’s why we’re launching a new project to find affordable fun in SLO County. We want to bring you along for the journey. I ...

The Bombardier Global 7500 just broke its 100th speed record, but with all the amenities onboard, writer Stefanie Waldek ...

A San Luis Obispo County park is one step closer to fruition. In the second phase of a three part plan, The Land Conservancy ...

SAN LUIS OBISPO, Calif. (AP) Isaac Jessup's 21 points helped Cal Poly defeat Cal State Bakersfield 98-72 on Saturday.